On 24 November 2021, HRA UK has updated that the Combined review will come into effect for all Clinical Trials of Investigational Medicinal Products (CTIMPs) from 1 January 2022. It was initially run as a pilot that started in 2018 under the name ‘Combined Ways of Working’ (CWoW) but from January 2022 it will be the only way to submit CTIMPs to MHRA and REC. Applications will be completed and submitted in the new part of IRAS.
To facilitate the transition there will be 3 webinars held-Combined Review as an Applicant, Combined Review for Sponsors, and Combined Review for NHS/HSC Participating Organisations. The webinars will provide an introduction to upcoming changes, help check the impact of the changes on the organization so as to update any internal processes/procedures as required thereof and provide guidance to available resources for further information and support.